Your liver can regenerate even after losing most of its mass

The liver is uniquely regenerative; it can regrow to full size after a large portion is removed, which is what makes living-donor transplants possible. Most organs cannot regrow lost tissue, but the liver is a prominent exception. Removing up to about two thirds of it surgically still leaves enough surviving cells to rebuild the organ back toward its original size over the following weeks. Regeneration here means the liver's own cells rapidly multiply to restore mass and function, rather than the remaining tissue simply growing larger, and the regrown liver does not perfectly recreate its original shape. This capacity is what makes living-donor liver transplants possible: a portion from a healthy donor can be removed and transplanted, and both the donor's remaining liver and the transplanted section regrow independently in their new hosts. The exact biological trigger that tells the liver when to stop regrowing is still an active area of research.

Your liver can regenerate even after losing most of its mass

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